Reaction of calcium phosphate cements with different amounts of tetracalcium phosphate and dicalcium phosphate anhydrous

Author(s):  
Kunio Ishikawa ◽  
Shozo Takagi ◽  
Laurence C. Chow ◽  
Kazuomi Suzuki
2013 ◽  
Vol 14 (1-2) ◽  
Author(s):  
Sabine Wächter ◽  
Claus Moseke ◽  
Jürgen Groll ◽  
Uwe Gbureck

AbstractThis study aimed to produce nanosized secondary calcium phosphate powders (CaHPO


Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3272
Author(s):  
Claudia Morilla ◽  
Elianis Perdomo ◽  
Ana Karla Hernández ◽  
Ramcy Regalado ◽  
Amisel Almirall ◽  
...  

Calcium phosphate cements have the advantage that they can be prepared as a paste that sets in a few minutes and can be easily adapted to the shape of the bone defect, which facilitates its clinical application. In this research, six formulations of brushite (dicalcium phosphate dihydrated) cement were obtained and the effect of the addition of sodium alginate was analyzed, such as its capacity as a tetracycline release system. The samples that contain sodium alginate set in 4 or 5 min and showed a high percentage of injectability (93%). The cements exhibit compression resistance values between 1.6 and 2.6 MPa. The drug was released in a range between 12.6 and 13.2% after 7 days. The antimicrobial activity of all the cements containing antibiotics was proven. All samples reached values of cell viability above 70 percent. We also observed that the addition of the sodium alginate and tetracycline improved the cell viability.


2001 ◽  
Vol 16 (1) ◽  
pp. 171-178 ◽  
Author(s):  
L. Leroux ◽  
J. L. Lacout

A new route, based on the use of ionic calcium phosphate cements, has been developed to synthesize hydroxyapatite. Cements were prepared from tetracalcium phosphate, α–tricalcium phosphate, phosphoric acid, strontium nitrate, and water. They were then mixed and shaped. Cements with various amounts of strontium and different (Ca + Sr)/P atomic ratios were prepared. All the materials obtained were coherent and solid. When the amount of strontium was low, mixed hydroxyapatite was obtained at low temperatures. Mixed calcium strontium apatite was obtained after heating. This original method can be of interest in various fields such as biomaterials or the storage of radioactive waste.


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